SOLITHROMYCIN INHIBITS IL-13-INDUCED GOBLET CELL HYPERPLASIA AND MUC5AC, CLCA1, AND ANO1 IN HUMAN BRONCHIAL EPITHELIAL CELLS

Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells

Solithromycin is a novel fluoroketolide antibiotic belonging to the class of macrolide antibiotics.Activation of the interleukin (IL)-13 receptor leads to STAT6 activation and subsequent induction of SAM pointed domain containing Body Skin Oil ETS transcription factor (SPDEF), chloride channel accessory 1 (CLCA1), and anoctamin-1 (ANO1), all of whi

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OWNERSHIP RETENTION, REPUTASI AUDITOR, LABA PERUSAHAAN, DAN UNDERPRICING TERHADAP NILAI PERUSAHAAN DENGAN KEPEMILIKAN MANAJERIAL DAN INSTITUSIONAL SEBAGAI VARIABEL MODERASI

Penelitian ini bertujuan untuk menguji pengaruh retensi kepemilikan (OR), reputasi auditor, laba perusahaan dan under pricing pada nilai perusahaan setelah penawaran umum perdana dan pengaruh moderating kepemilikan manajerial dan variabel kepemilikan institusional pada hubungan antara proporsi kepemilikan dengan nilai perusahaan setelah penawaran u

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On Some Rare Coins from the Khwarezm Hoard of 13th Century

Two silver dirhams Heating Rods of Khwarezm, dated to 670 AH/1271AD, with an unusual tamga are analyzed in the article.The coins come from a hoard located in the territory of Turkmenistan, the exact place of discovery being unknown.On both coins under consideration, a new, previously unknown type of tamga has been discovered.Typologically, it belon

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